10 Most Prescribed Drugs

According to Dr. Lesar, "This analgesic can have issues related to overuse and misuse."

Side effects could also include increased potassium in the blood or too much of a drop in blood pressure.

Other side effects could include constipation and fluid accumulation in legs leading to swollen ankles.

Azithromycin (Z-Pak/Zithromax): ''This is an antibiotic with modest drug interactions. says Dr. Lesar, advising only against taking antacids that contain aluminum or magnesium within two hours of taking azithromycin.

Used for treating bacterial infections, such as infection of the lungs, nasal passages or pneumonia, it can often cause nausea.

More unusual side effects include an abnormal heart rhythm or severe skin rash.

While there are no major drug interactions, side effects can include nausea and diarrhea, and in some cases, it may make birth control pills less effective.

Generic Glucophage (metformin): This drug is used to treat type 2 diabetes and should be avoided by anyone with poor renal function, as it could result in gastrointestinal upset.