Europa League official line-ups: Roma vs. Bologna
Roma look to Donyell Malen and Stephan El Shaarawy for the Europa League all-Italian derby, as Bologna trust Santiago Castro and Federico Bernardeschi.
It kicks off at the Stadio Olimpico at 20.00 GMT (21.00 CET).
The first leg ended 1-1 at the Stadio Dall’Ara, meaning it is all to play for in the Eternal City for a place in the Europa League quarter-finals.
Whoever wins will go through to face either Aston Villa or Lille.
Roma continue to have a serious injury crisis, missing Paulo Dybala, Matias Soulé, Artem Dovbyk and Evan Ferguson, while Lorenzo Venturino is not on the UEFA list.
Stephan El Shaarawy is chosen to start in support of centre-forward Malen, despite Lorenzo Pellegrini scoring in the first leg.
Once again, Bryan Cristante and Niccolò Pisilli will share the task of pushing into a more advanced position from midfield at different times in the game.
It has been a difficult period for Roma, who managed just two draws in four competitive games, sliding from fourth to sixth in the Serie A table.
Bologna have problems too, because Juan Miranda is suspended, while former Roma goalkeeper Lukasz Skorupski is ruled out after picking up an injury at the weekend in the Serie A their 1-0 victory away to Sassuolo.
It means Federico Ravaglia has to take over the gloves, while Nikola Moro is not at 100 per cent and Lorenzo De Silvestri isn’t on the UEFA list.
Once again, Riccardo Orsolini is left on the bench, as Bernardeschi and Jonathan Rowe are in fine form supporting Castro upfront.
The Stadio Olimpico is a special place for Bologna, as this is where they beat Milan last season to win the Coppa Italia and qualify for the Europa League.
When these sides met here in Serie A back in August 2025, it ended 1-0 for Roma with a Wesley goal on his debut.
Roma vs. Bologna line-ups
Roma: Svilar; Mancini, Ndicka, Hermoso; Celik, Koné, Pisilli, Wesley; Cristante; El Shaarawy, Malen
Roma bench: De Marzi, Gollini, Rensch, Pellegrini, El Aynaoui, Tsimikas, Ziolkowski, Vaz, Ghilardi, Zaragoza
Bologna: Ravaglia; Zortea, Vitik, Lucumì, Joao Mario; Ferguson, Freuler, Pobega; Bernardeschi, Castro, Rowe
Bologna bench: Pessina, Franceschelli, Moro, Orsolini, Heggem, Casale, Odgaard, Lykogiannis, Sohm, Dallinga, Cambiaghi, Dominguez
Ref: Kovacs (ROU)