Ntamack set for Toulouse return at Bordeaux-Begles
Ntamack missed the Six Nations having been sidelined since December.
A possible return in February was delayed due to a hamstring issue but he is set to feature at Bordeaux-Begles in Sunday's re-run of last season's Top 14 final.
Record 24-time French champions Toulouse are likely to be without Les Bleus scrum-half Antoine Dupont and full-back Thomas Ramos.
Dupont and Ramos, who kicked the Six Nations-winning penalty in Saturday's 48-46 victory over England, are in line to be rested.
There are doubts around back-rowers Anthony Jelonch and Joshua Brennan, as well as centre Pierre-Louis Barassi and prop Rodrigue Neti after the quartet also played as France won back-to-back Six Nations titles for the first time since 2007.
Leaders Toulouse have a 12-point advantage over second-placed Pau, with Bordeaux-Begles in fifth.