Rob Reiner, director of 'The Princess Bride,' is dead at 78

• Director Rob Reiner and his wife were found dead in their home in Los Angeles on Sunday.
• In a Sunday night statement, LA's mayor confirmed the Reiners' deaths and an ongoing investigation.
• Reiner's films include "This is Spinal Tap," "The Princess Bride," and "When Harry Met Sally."

Rob Reiner, the award-winning director of "When Harry Met Sally" and "The Princess Bride," and his wife, Michele Singer Reiner, were found dead in their home on Sunday.

A Los Angeles Police Department representative told Business Insider that at 3:38 p.m. on Sunday, the department received a medical aid call to the 200 Block of Chadbourne Avenue in Brentwood, Los Angeles.

At the scene, the LAPD determined the deaths of a 78-year-old man and 68-year-old woman. The LAPD said in an X statement that its Robbery Homicide Division was investigating an apparent homicide.

In a Sunday night statement, LA Mayor Karen Bass confirmed the Reiners' deaths and said that the investigation was ongoing.

LAPD Deputy Chief Alan Hamilton said in a Sunday night press conference that the department was not seeking anyone as a suspect or person of interest in the case, and that the LAPD would speak with the couple's family members in the investigation.

Representatives for the family did not immediately respond to Business Insider's requests for comment.

Former House Speaker and California Rep. Nancy Pelosi said in an X post on Sunday that the news was "devastating."

"It's hard to think of anyone more remarkable and excellent in every field and endeavor they pursued," Pelosi wrote.

She added, "Rob was creative, funny, and beloved. And in all of their endeavors, Michelle was his indispensable partner, intellectual resource, and loving wife."

Reiner had a long and illustrious career in Hollywood. The son of actor, director, and screenwriter Carl Reiner, he studied at the UCLA Film School before starting his directing journey.

He directed several iconic Hollywood movies, including "This is Spinal Tap" in 1984, "The Princess Bride" in 1987, and "When Harry Met Sally" in 1989.

Reiner also appeared in several acting stints, including movies such as the 2013 Martin Scorsese blockbuster "The Wolf of Wall Street" and TV series "New Girl" and "The Bear."

In 1987, he founded Castle Rock Entertainment, a production company, alongside a group of film producers. The company is now a subsidiary of Warner Bros. Discovery.

Reiner and his wife had three children together: Nick, Jake, and Romy Reiner. He has one daughter, Tracy Reiner, from his previous marriage to actor Penny Marshall.

Nick Reiner battled drug abuse in his teens and early adulthood. His experience, including stints in rehab, led him to write the screenplay for "Being Charlie," a 2015 romance-drama that his father directed.

In 2016, Reiner told Business Insider that his son was the "heart and soul of the film."