Prepare to be upset because March Madness has officially kicked off and fans from across the country are flocking to Las Vegas to join in on the commotion.

When it comes to putting money on the line, a couple of Las Vegas sportsbooks say the first week of March Madness is more popular than Super Bowl weekend.

"The opening weekend, including the playing games with March Madness, does about two times the amount of actual betting activity as the Super Bowl," said Caesar’s Entertainment Lead of College Basketball Rich Zanco.

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Sixty-eight schools are on the line the first weekend of March Madness, and fans come in from all over to cheer on their team.

"You got a lot of these bettors and fans of these teams that are alumni of these universities and schools. So there's always upsets, there's always cheering and a raucous crowd. People are getting their pour on probably at 9 a.m. early in the morning," said Zanco.

The American Gaming Association predicts fans will bet a whopping $3.1 billion dollars on the tournaments this year – which is up $400 million from last year.

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"As more states get on board, you start to see the betting interest and fever growing. So it's grown from people just filling out brackets to having maybe a little office pool to now they're able to get on a phone app or whatever the case may be or going to their sportsbook," said Zanco.

While sports betting is legal in more states than ever, Las Vegas is still a hot spot to enjoy the tournament.

"It might seem counterintuitive that it benefits Nevada and Las Vegas to have so many states have legalized gambling and sports wagering. But it's actually a good thing in that it's almost a training ground for folks now that more can get involved in this form of entertainment," said Circa VP of Operations Mike Palm.

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But, even with more training, the odds of building a perfect bracket are still close to zero.

"It's estimated to be 120 billion to one. If it was just, you know…if there was total randomness to it, like you were flipping a coin 67 times, it's over a kajillion to one," said Palm.

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Besides brackets, some fun prop bets here in Vegas include: which state or conference will win the championship, and which of the lower-seeded schools will win a game. 

Tuchel will resist the temptation to make sweeping changes for England's World Cup qualifier against Latvia

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THOMAS TUCHEL will show no mercy to Prem bosses by refusing to rest England stars.

And that is because the Three Lions chief says his club counterparts do not care about international managers.

Tuchel will resist the temptation to make sweeping changes for tonight’s World Cup qualifier against Latvia at Wembley.

He insists his coaches will not ‘break our heads’ worrying about rotation — pointing out Arsenal boss Mikel Arteta did not rest Declan Rice for a Champions League tie with PSV Eindhoven.

The German said: “Given the fact Declan Rice played in the second leg with Arsenal after a 7-1 first-leg lead, I didn’t have the feeling they think so much about us.

“So I don’t think we have to break our heads about this.

“I take care of the players. We take care about the schedule.  But it would be the wrong signal to tell players now ‘you have tough (club) matches coming up, so I rest you now’.

“We have a qualifier to play, we do what’s good for us. We are in contact with the clubs, we are in high-level monitoring where the fitness statuses are known and we won’t take any unprofessional risks.”

Manchester City boss Pep Guardiola had ‘never been so angry’ as when John Stones returned injured after Tuchel’s predecessor Gareth Southgate started the defender in two England friendlies in four days last year.

But Tuchel claims he never asked players to skip internationals while manager of Chelsea, Paris Saint-Germain and Bayern Munich, where he managed  Harry Kane.

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He said: “This window is at a time where clubs play a crucial part of the season.

“They play for championships and  quarter-finals in the Champions League. We’re well aware of it but we also have our own goals and targets. The players are keen to play and it has to be like this.

'I don't expect anything' Roy Keane savages England star after below-par display in Thomas Tuchel's first game

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“I never pushed any national coach because I hoped my players did get picked, I was also hoping they are proud to play.

“You’re never happy if something happens. No one can predict there is no accident, but  we’ll take responsible decisions.

“I feel responsible for the players. I want the players to play in the quarter-finals of the Champions League — all of them — because I want to watch it.”

A hip injury has forced Anthony Gordon to return to Newcastle for treatment.

The winger, 24, limped off down the tunnel after Friday’s 2-0 win over Albania.